Hormonal and clinical dataset of women with amenorrhea and delayed menstruation in the Kurdistan Region of Iraq

Description

The information presented in this study describes the endocrine profiles of 25 women (aged 14–50) from the Kurdistan region of Iraq who exhibit amenorrhea or delayed menstruation. The five primary hormonal causes found in the data are Polycystic Ovary Syndrome (PCOS), Thyroid Dysfunction, Diminished Ovarian Reserve (Low AMH), Ovarian Insufficiency (elevated FSH/LH), and Hyperprolactinemia.

Steps to reproduce

Steps to Reproduce: 1. Participant Selection: Identify women (aged 15–48) diagnosed with amenorrhea or delayed menstruation. In this study, 25 participants were recruited from gynecological clinics across the Kurdistan region of Iraq. 2. Clinical Screening: Perform initial diagnostic evaluations using Magnetic Resonance Imaging (MRI) and Ultrasonography (U/S) to identify structural abnormalities (e.g., PCO morphology, hypoplastic uterus). 3. Sample Collection: Collect venous blood samples into Serum Separator Tubes (SSTs) containing a gel barrier. 4. Serum Processing: Allow the blood to clot naturally, then centrifuge the samples at 3,000 g for 10 minutes to isolate the serum. Store aliquoted serum at -80°C until analysis. 5. Hormonal Profiling: Use the Cobas e 411 automated immunoassay analyzer (Roche Diagnostics) to quantify target biochemical parameters including Prolactin, FSH, LH, AMH, TSH, T4, and Testosterone. 6. Assay Protocol: Follow the manufacturer’s specifications for each reagent kit. The total assay time is approximately 25 minutes per sample. 7. Data Analysis: Categorize results based on hormonal reference ranges to identify etiologies such as Hyperprolactinemia, Ovarian Insufficiency, PCOS, and Thyroid Dysfunction.

Institutions

• Koya University

  Erbil, Erbil

Categories

Licence