Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis

Published: 30 July 2018| Version 2 | DOI: 10.17632/8d5hgmvhjm.2
Contributors:
Nam Chu, Antonieta Salguero, Sandra Gabelli, Philip Cole

Description

This dataset includes additional results for production of semisynthetic Akt1 proteins, and biochemical, enzymological assays in the paper. The original data for kinase and affinity binding assays are also uploaded.

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Institutions

Johns Hopkins University Department of Pharmacology and Molecular Sciences, Johns Hopkins University Department of Biophysics and Biophysical Chemistry, Brigham and Women's Hospital Department of Medicine, Harvard Medical School Department of Biological Chemistry and Molecular Pharmacology

Categories

Protein Kinase, Phosphorylated Protein, X-Ray Crystallography, Protein Chemistry, Biomedical Research

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