dataset for HLA Class II-restricted CD8+ T cells contribute to the promiscuous immune response in dapsone hypersensitive patients

Published: 4 August 2020| Version 1 | DOI: 10.17632/8n5gpj88xx.1
Contributor:
Dean Naisbitt

Description

Our data shows that , dapsone and nitroso dapsone interact with a number of HLA molecules to activate CD8+ TCC, with HLA class-II-restricted CD8+ TCC that display hybrid CD4/CD8 features also contributing to the promiscuous immune response that develops in patients. Uploaded are the raw spreadsheets showing results from T-cell clone proliferation data stimulated with drugs

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Institutions

University of Liverpool

Categories

Drug Allergy, T-Cell Response

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