Recruitment of Fpt1 to tRNA genes requires TFIIIB and the N-terminal TPR array of TFIIIC subunit τ131

Published: 25 December 2025| Version 1 | DOI: 10.17632/9g7jd5jxc6.1
Contributor:
F van Leeuwen

Description

Figure 2. The IDR of Fpt1 encodes a nuclear localization signal and stress-responsive element, while the core domain ensures protein stability. Figure 3. A small region in the disordered region is predicted to interact with τ131 and responsible for the stress response. Figure 4. The N-terminal TPR array of τ131 mediates the stress response of Fpt1. To open microscopy images, drag the Pos0 folder to ImageJ.

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Institutions

  • Antoni van Leeuwenhoek Nederlands Kanker Instituut

Categories

Fluorescence Microscopy, Western Blot

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