Dataset- Systematic Review, Pairwise and Network Meta-Analysis for Restorative and Adhesive Strategies for Cervical Carious Lesions
Description
This dataset supports a systematic review and network meta-analysis aimed at evaluating the clinical effectiveness of various restorative materials and adhesive strategies used in the management of cavitated cervical carious lesions in adult patients. The included randomized controlled trials (RCTs) were identified through comprehensive searches in five major databases and selected according to predefined eligibility criteria based on the PICO framework. The primary outcome assessed was the clinical retention of restorations, stratified by material type and adhesive protocol. The dataset comprises extracted data on study characteristics, intervention types, follow-up durations, outcome measures, and risk of bias assessments. It includes subgroup analyses, pairwise meta-analyses, and a frequentist network meta-analysis (NMA), along with confidence evaluations using the CINeMA framework. While compomer-based restorations showed the highest clinical success rates in pairwise analyses, the NMA indicated that these results were derived from trials with high risk of bias, thus limiting the reliability of the evidence. In contrast, restorations using conventional composite resin with a two-step etch-and-rinse adhesive (2ER/CC) demonstrated consistent and durable performance, supported by studies of higher methodological quality. As such, 2ER/CC emerged as the most evidence-supported option for long-term management of cervical carious lesions. This dataset includes the raw data tables, R scripts for statistical analysis (using meta, netmeta, ggplot2, and dplyr packages in R), and the complete risk of bias and CINeMA assessments, offering a valuable resource for replication, secondary analyses, or future updates of this review.
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Institutions
- Universidad Autonoma de Chile
- Universidad de Ciencias Medicas de La Habana