Supplemental Tables - Accelerated osteocytic citrate production in chronic kidney disease is associated with protection of the kidney
Description
Supplemental Tables for manuscript: "Accelerated osteocytic citrate production in chronic kidney disease is associated with protection of the kidney". Datasets: Table S1: Differentially expressed genes in tibia cortices of control and AdKI mice (n=3 per group), analyzed via RNASeq and the Deseq2 algorithm. Table S2: Extracellular 13C-labeling of metabolites within spent media of osteocyte-enriched femora (Ocy-Fem) and osteocyte-enriched calvariae (Ocy-Cal) following 24h of ex vivo culture in [1,2-13C]-glucose (n=5 per group). Table S3: Intracellular 13C-labeling of metabolites extracted from osteocyte-enriched femora (Ocy-Fem) and osteocyte-enriched calvariae (Ocy-Cal) following 24h of ex vivo culture in [1,2-13C]-glucose (n=5 per group). Note: At the start (time 0h), it is assumed that M0 fragments predominate (100%) and no 13C-enrichment has taken place yet. Data at 9h and 24h are extracted from ex vivo cultured osteocyte-enriched bone organs. Table S4: Extracellular 13C-labeling of metabolites within spent media of osteocyte-enriched femora (Ocy-Fem) following 24h of ex vivo culture in [1,2-13C]-glucose or [U-13C]-glutamine (n=5 for control and AdKI WT mice; n=4 for control and AdKI Slc13a5R337*/R337* mice). (Accepted manuscript for publication in a peer-reviewed journal may differ)
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- University of Michigan School of Dentistry