Adhesion extent data for rabbit Achilles tendon full transection model repaired with a 4-strand Becker suture, an additional DegraPol® tube or an additional DegraPol® tube releasing stem cell/tenocyte secretome plus an initial injection of secretome

Published: 11 September 2025| Version 1 | DOI: 10.17632/9wy3w6cykn.1
Contributor:
Johanna Buschmann

Description

Here we present adhesion extent data gathered from a rabbit Achilles tendon full transection model. We assessed how much of the tissue adhered to the surrounding tissue in cross sections of the rabbit Achilles tendons three weeks post operation compared to the entire circumference. The experimental groups were a) a 4-strand Becker suture, b) a 4-strand Becker suture with a pure DegraPol® tube, c) a 4-strand Becker suture, an injection of 50 microliter of a secretome harvested from a 3:1-ratio cell culture of adipose-derived stem cells:rabbit Achilles tenocytes, and a DegraPol® tube releasing such secretome, and d) the non-treated healthy rabbit Achilles tendons as a control.

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Steps to reproduce

Method found in the following article: V. Tan; A. Nourbakhsh; J. Capo; J.A. Cottrell; M. Meyenhofer; J.P. O'Connor. Effects of Nonsteroidal Anti-Inflammatory Drugs on Flexor Tendon Adhesion. Journal of Hand Surgery-American Volume 35A (2010) 941-947. doi:10.1016/j.jhsa.2010.02.033

Institutions

  • Universitat Zurich
  • UniversitatsSpital Zurich

Categories

Fibrosis, Adhesion, Achilles Tendon, In Vivo Study

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