Vitamin D supplementation and cardiac function.

Published: 11 September 2019| Version 1 | DOI: 10.17632/b98drwjsr2.1
Matteo Briguglio


Raw data of the clinical trial NCT03403933. We enrolled 47 older adults scheduled for major orthopaedic surgery and suffering from hypovitaminosis D. Patients underwent 6-months calcifediol supplementation with a starting dose at first post-operative day of 50 µg/die in liquid preparation. Down-titration to 20 µg/die at 3-months assessment was planned. Cardiac performance was evaluated by measuring left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) during pre-operative assessments and at 1-month, 3-months, 6-months follow-ups. The dataset was used to write the article "Correction of hypovitaminosis D improved global longitudinal strain earlier than left ventricular ejection fraction in cardiovascular older adults after orthopaedic surgery", which was published by the Journal of Geriatric Cardiology in 2018.



IRCCS Istituto Ortopedico Galeazzi


Vitamin D, Echocardiography of Left Ventricular Function, Orthopedics Surgery, Hearth