A pathogen peptidoglycan scaffold coated with artificial biomembrane promotes broad resistance to bacterial infections by dynamically reprogramming macrophage metabolism.
Published: 25 April 2025| Version 1 | DOI: 10.17632/bgpcsxzgw3.1
Contributor:
junjie guoDescription
The data includes LM@pBLP Characterization experiments, particle size and potential, transmission electron microscopy, Fourier transform infrared spectroscopy, flow cytometry, safety experiments. LM@pBLP Induced rapid protection, broad-spectrum protection, long-lasting protection, in vitro macrophage experiments, mouse in vivo experiments, and in vitro macrophage experiments. Measure the expression levels of cytokines and training immune markers using qPCR. Measure the concentrations of lactate, glucose, ROS, and NO in the supernatant and serum of mouse cells using a detection kit. Survival rate and weight changes of mice.
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Animal, Preventive Medicine, Biological Material