SLRC_LsPtx

Published: 28 October 2022| Version 1 | DOI: 10.17632/bh9cg59mw5.1
Contributors:
Oystein Evensen, Elisabeth Gislefoss,
,

Description

Sequence data for two different peroxinectins in salmon lice, Lepeophtheirus salmonis. Obtained antibody responses post vaccination. Data from challenge with infective stages of L salmonis in naive and vaccinated fish with counting of lice numbers at moveable stages. Data show that one of the peroxinectins are indispensable for lice development. Vaccinated fish have reduced numbers of sea lice attached post vaccination and challenge but not down to significant reduction.

Files

Steps to reproduce

Sequencing of two peroxinectins from sea lice (Lepeophtheirus salmonis), tested for importance of lice development through RNAi studies, gene cloned and used in expression vector for vaccination. Recombinant protein used for boost. Collected plasma to assess immune responses post vaccination and performed studies to correlate to reduction in lice numbers.

Institutions

Norges miljo- og biovitenskapelige universitet Institutt for plantevitenskap, Universitetet i Bergen

Categories

Veterinary Parasite Immunology

Licence