Neutralization Data and Aligned ENV Sequences for Predicting Antibody Affinities using Artificial Neural Networks
Sample file with neutralization data (IC50) for different antibodies and viral strains, adapted from J. Huang, G. Ofek, L. Laub, M. K. Louder, N. A. Doria-Rose, N. S. Longo, H. Imamichi, R. T. Bailer, B. Chakrabarti, S. K. Sharma, S. M. Alam, T. Wang, Y. Yang, B. Zhang, S. A. Migueles, R. Wyatt, B. F. Haynes, P. D. Kwong, J. R. Mascola, and M. Connors, “Broad and potent neutralization of HIV-1 by a gp41-specific human antibody.,” Nature, vol. 491, no. 7424, pp. 406–12, Nov. 2012. Aligned ENV sequences downloaded from the HIV Sequence Database (www.hiv.lanl.gov/content/sequence/HIV/mainpage.html). There are 4907 sequences and the alignment length is 1369.