Örd et al 2025 Supplementary Data and Code

Published: 25 July 2025| Version 4 | DOI: 10.17632/bs54ny7ns2.4
Contributor:
Mihkel Örd

Description

Supplementary Data and Code accompanying manuscript by M. Örd et al entitled “High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants”. Supplementary Data 1 Description: Experimental data for the cell cycle protein peptide tiling SIMBA pooled screens. Supplementary Data 2 Description: The cyclin binding motifs identified in the cell cycle protein peptide tiling SIMBA experiment. Supplementary Data 3 Description: Experimental data for mutational scanning SIMBA pooled screens. Supplementary Data 4 Description: Median SIMBA scores and p-values for mutational scanning SIMBA experiments. Supplementary Data 5 Description: DMS data from two distinct libraries (library 1 and library 2) that were tested independently. Supplementary Data 6 Description: Combined set of cyclin binding motifs from peptide tiling and mutational scanning SIMBA experiments.

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Molecular Biology, Cell Cycle, Cyclin-Dependent Kinase, Protein-Protein Interaction, High-Throughput Screening

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