Psychological Assessment of Anxiety and Depression in Patients with Single versus Multiple Keloids: A Cross-Sectional Study

Published: 12 May 2026| Version 1 | DOI: 10.17632/bydxsgzyrr.1
Contributors:
Lian Zhang, Yanyu Du, Dan Sun, Peipei Huang, Renliang He, Bin Yang

Description

Supplementary Figure Legends Supplementary Figure 1. Flowchart of patient enrollment and grouping. Supplementary Figure 2. Comparison of psychological distress scores between patients with single versus multiple keloids. (A) Total Hospital Anxiety and Depression Scale (HADS) scores (p=0.015). (B) Self-Rating Anxiety Scale (SAS) scores (p=0.062). (C) Self-Rating Depression Scale (SDS) scores (p=0.003). Patients with multiple keloids exhibited significantly higher levels of depression. Supplementary Figure 3. Comparison of physical symptom burden between single and multiple keloids. Vancouver Scar Scale (VSS) scores (p<0.001) and Visual Analog Scale (VAS) scores (p<0.001). Paradoxically, single keloid patients reported significantly higher localized physical symptom scores.. Supplementary Figure 4. Correlation Analysis between psychological distress and physical symptoms. Scatter plots showing the relationship between psychological scores (HADS, SAS, SDS) versus physical symptoms (VSS and VAS). No significant correlation was found between physical symptom severity and psychological distress across the cohort (all correlation coefficients R < 0.1, p > 0.05).

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Dermatology, Keloid

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