Application of HPMCAS-coated Ctx(Ile21)-Ha peptide microparticles as a potential use to prevent systemic infection caused by Salmonella Enteritidis in poultry

Published: 21 June 2021| Version 3 | DOI: 10.17632/cgkt7pxj2n.3
Contributors:
Cesar Augusto Roque Borda, Mauro de Mesquita Souza Saraiva, Daniel F. M. Monte, Lucas Bocchini Rodrigues Alves, Adriana Maria de Almeida, Taísa Santiago Ferreira, Túlio Spina de Lima, Valdinete Pereira Benevides, Julia Memrava Cabrera, Andréia Bagliotti Meneguin, Marlus Chorilli, Angelo Berchieri Junior, Eduardo Festozo Vicente

Description

Randomly distributed 40 laying hen chicks per group, including control group A (no Ctx(Ile21)-Ha; n=40), B (2.5 mg of Ctx(Ile21)-Ha/kg; n=40), and C (5 mg of Ctx(Ile21)-Ha/kg; n=40) were performed. Laying hen chicks were orally infected with 0.2 mL (108 CFU/mL) of S. Enteritidis.

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Steps to reproduce

Fisher’s exact test was used to compare Salmonella excretion on the feces between the groups (P< 0.05). While the logarithmically transformed values for bacterial counts from cecal content, liver, and spleen, were submitted to two-way ANOVA followed by Bonferroni multiple comparison test (P < 0.05). All statistical analyses were performed using the software GraphPad Prism, version 8.2.1.

Institutions

  • Universidade Estadual Paulista Julio de Mesquita Filho

Categories

Biotechnology, Animal Science, Pharmaceutics

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