Source data for: MT2A buffering exhaustion drives cuproptosis
Description
Source data for figures and tables. Manuscript: FRBM-S-26-00079.
Files
Steps to reproduce
1. Download the Source_Data2.xlsx file, which contains source data for all figures and tables in the manuscript. 2. Each sheet in the Excel file corresponds to a specific figure or table (e.g., Figure_1A, Figure_2C), with column headers describing the variables. 3. For bioinformatics analyses (scRNA-seq, LASSO, Mendelian randomization, etc.), the raw sequencing datasets are publicly available at NCBI GEO under the following accession numbers: - GSE145926 (COVID-19 BALF) - GSE147507 (SARS-CoV-2 infected cells) - GSE151263 (Sepsis PBMC) - GSE158055 (BALF scRNA-seq) - GSE185263 (Lung ARDS) - GSE212865 (Clinical validation cohort) 4. Statistical analyses and visualization were performed in R (v4.x). Figures can be reproduced using the source data provided and standard R packages (Seurat, ggplot2, survival, glmnet). 5. Detailed methods are described in the Materials and Methods section of the manuscript.