Simulated Microgravity-Induced Alterations in PDAC Cells: A Potential Role for Trichostatin A in Restoring Cellular Phenotype

Name: Simulated Microgravity-Induced Alterations in PDAC Cells: A Potential Role for Trichostatin A in Restoring Cellular Phenotype
Creator: Corinna Pagano
Published: 2025-04-09T07:17:56.756Z
Keywords: Cell (Life Sciences)

Pagano, Corinna; Masini, Maria Angela; Sabbatini, Maurizio; Gribaudo, Giorgia; Manfredi, Marcello; Caprì, Flavia; Bonetto, Valentina; Magnelli, Valeria; Donadelli, Massimo; Corino, Roberto; Belay, Masho; Robotti, Elisa; Marengo, Emilio

doi:10.17632/cn22f6pkzv.1

Simulated Microgravity-Induced Alterations in PDAC Cells: A Potential Role for Trichostatin A in Restoring Cellular Phenotype

Published: 9 April 2025| Version 1 | DOI: 10.17632/cn22f6pkzv.1

Contributors:

Corinna Pagano, Maria Angela Masini,

, Giorgia Gribaudo, Marcello Manfredi, Flavia Caprì, Valentina Bonetto, Valeria Magnelli, Massimo Donadelli, Roberto Corino, Masho Belay, Elisa Robotti, Emilio Marengo

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The work involves molecular and proteomic analysis investigating cell growth, metabolism, and protein synthesis after TSA treatment in three-dimensional organized PaCa44 cells (cell spheroids) following microgravity exposure

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Universita degli Studi del Piemonte Orientale Amedeo Avogadro Sede di Alessandria

Simulated Microgravity-Induced Alterations in PDAC Cells: A Potential Role for Trichostatin A in Restoring Cellular Phenotype

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