Histological and molecular analises of cutaneous leishmaniasis in experimental model (Mesocricetus auratus)
Published: 23 July 2026| Version 1 | DOI: 10.17632/d5h5zb7g47.1
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, Description
To study parasite distribution in leishmaniasis cutaneous lesions 31 Golden hamsters were infected with L. (Viannia) braziliensis promastigotes and followed-up until the development of an ulcerated lesion. Samples were collected from perilesional region and intralesional region and the following analyses was performed: 1) Quantification of parasite load by kDNA qPCR 2) Relative quantification of 7SRLNA transcripts by RT-qPCR 3) Histological analyses by hematoxilin and eosin 4) Immunohistochemistry (IHC) analyses
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Parasitology, Diagnosis, Cutaneous Leishmaniasis