EEG correlates of psychoactive ketamine: Comparing spectral power and complexity

Published: 24 February 2026| Version 2 | DOI: 10.17632/dmk2dmzzwn.2
Contributor:
Brandon Reynante

Description

Data and scripts for analyzing and visualizing spectral power and complexity of spontaneous EEG signals in normal waking and psychoactive ketamine states. Re-analyzes EEG data from a publicly available dataset (must be downloaded separately): Farnes, N., et al. (2020). Increased signal diversity/complexity of spontaneous EEG, but not evoked EEG responses, in ketamine-induced psychedelic state in humans. PLOS ONE, 15(11), e0242056. https://doi.org/10.1371/journal.pone.0242056 https://datadryad.org/dataset/doi:10.5061/dryad.j9kd51c9q 11D-ASC.csv: participant retrospective ratings of phenomenology using the 11D-ASC instrument Ketamine_EEG_complexity.m: MATLAB script for computing EEG signal complexity lzw.m: MATLAB function for Lempel-Ziv-Welch algorithm (from https://github.com/iulia-m-comsa/EEG/tree/master/Lempel-Ziv%20complexity) lzwNormalised.m: MATLAB function for Lempel-Ziv-Welch algorithm (from https://github.com/iulia-m-comsa/EEG/tree/master/Lempel-Ziv%20complexity) Ketamine_EEG_power.m: MATLAB script for computing EEG spectral power Ketamine_EEG_phenomenology.m: MATLAB script for computing correlations between 11D-ASC scores and changes in spectral power and complexity Ketamine_EEG_visualization.m: MATLAB script for visualizing the results plot_topography.m: MATLAB script for plotting scalp topographies (from https://www.mathworks.com/matlabcentral/fileexchange/72729-topographic-eeg-meg-plot) MEG_Yokogawa-440ag.mat: MATLAB file required for plotting scalp topographies Standard_10-10_47ch.mat: MATLAB file required for plotting scalp topographies Standard_10-20_81ch.mat: MATLAB file required for plotting scalp topographies

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Neuroscience, Neuropharmacology

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