SPIKES: Identification of physicochemical properties of spike proteins across diverse host species of SARS-CoV-2. Yerukala Sathipati et al.
Published: 6 May 2022| Version 1 | DOI: 10.17632/dwjc8bwhws.1
Contributors:
Srinivasulu Yerukala Sathipati, Description
To determine the significance of compositional changes in amino acids in S proteins from different strains of CoVs, we compared changes between Rousettus bat coronavirus (GenBank: AOG30822.1) and hCoV/wuhan/WIV05/2019 strain using the hCoV-19 spike glycoprotein mutation surveillance dashboard, GISAID. We used GISAID data statistics to examine the amino acid changes in the S protein that increased the infectivity in emerging new variants.
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Institutions
Marshfield Clinic
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COVID-19