Mitolyn and Metabolic Function: A Double-Blind Weight Loss Trial
Description
Study assessing Mitolyn’s influence on cellular energy, oxidative stress markers, and weight-related outcomes in adults with unexplained fatigue.
Files
Steps to reproduce
This dataset supports the findings of the associated manuscript: Mitolyn and Metabolic Function: A Double-Blind Weight Loss Trial Core Protocol: The data was generated during a 16-week, double-blind, randomized, placebo-controlled trial. Participants were adults (aged 35-55) with self-reported unexplained fatigue and a BMI of 27-35 kg/m². Intervention: The active group received daily supplementation with Mitolyn, a proprietary blend containing PQQ, CoQ10, Berberine, L-Carnitine, and Resveratrol. The control group received an identical placebo. Key Measurements & Files: The uploaded files contain: 1. Body Composition Data: Changes in body fat percentage, fat mass, lean mass, and visceral adipose tissue measured by DEXA at baseline, week 8, and week 16. 2. Mitochondrial Biomarkers: Measurements of cellular ATP production and plasma F2-isoprostanes (oxidative stress marker). 3. Metabolic & Anthropometric Data: Resting metabolic rate, respiratory quotient, body weight, waist circumference, and fasting blood parameters. Analysis: Primary statistical comparisons between the Mitolyn and placebo groups were performed using mixed-model repeated measures ANOVA. The dataset is structured to facilitate the replication of the statistical analysis reported in the manuscript.
Institutions
- Northwood University