The roles and signalling pathways of lncMALAT1 in coronary artery disease: A systematic review of in vivo and in vitro studies

Description

Figure 1 PRISMA flow diagram for systematic reviews. PRISMA : Preferred Reporting Items for Systematic Review and Meta-analysis Figure 2. Transcription and expression of MALAT1 involved in CAD animal of in vivo model. The effects of MALAT1 deficiency, overexpression, and knockdown focus on upstream and downstream signalling pathways, cardiac function, vascular changes, and potential therapeutic targets were demonstrated. Blue represents MALAT1 deficiency. Red represents overexpression of MALAT1. Green represents MALAT1 knockdown. ↑ represents upregulate. ↓ represents downregulate. Figure 3. Transcription and expression of MALAT1 involved in CAD in vitro model. The presentation of MALAT1 overexpression and knockdown highlighted upstream and downstream signalling pathways, cell function, vascular changes, and potential therapeutic targets were summarized. Red represents overexpression of MALAT1. Green represents MALAT1 knockdown. ↑ represents upregulate. ↓ represents downregulate.

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Funders

• Yunnan Provincial Science and Technology Department

  China

  Grant ID: 202201AT070277, 202305AD160059, 202102AA310003
• Health Science and Technology Project of Kunming

  Grant ID: 2022-SW-011

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