Supplementary Material for "Acantholytic disorders: Update on pathophysiology, diagnosis, and management"
Description
Supplementary Figure 1. Yellow-brown coalescing keratotic papules on the forehead and scalp in a patient with Darier disease. Supplementary Figure 2. Hyperkeratotic plaques with areas of erosion and crusting of the ear and preauricular skin in a patient with Darier disease. Supplementary Figure 3. Numerous erythematous keratotic papules of the inframammary region in a patient with Darier disease. Supplementary Figure 4. Splitting of the distal nail plate with red and white streaks in the nail bed in a patient with Darier disease Supplementary Figure 5. Dorsal tongue with a cobblestone pattern of papules in a patient with Darier disease. Supplementary Figure 6. Darier disease: Acantholytic dyskeratosis with corps ronds and grains (100X, H&E). Supplementary Figure 7. Darier disease: A biopsy shows suprabasal epidermal acantholysis and dyskeratosis (40X, H&E). Supplementary Figure 8. A vesiculated and eroded hyperpigmented plaque in a patient with Hailey-Hailey disease. Supplementary Figure 9. Erythematous and hyperpigmented plaque with vesiculation, erosion, and crusting in a patient with Hailey-Hailey disease. Supplementary Figure 10. A macerated and fissured erythematous plaque resembling wet torn tissue paper in the axilla of a patient with Hailey-Hailey disease. Supplementary Figure 11. Eroded pink plaques of the axilla with dyspigmentation in a patient with Hailey-Hailey disease. Supplementary Figure 12. Hailey-Hailey disease: Dilapidated brick wall appearance due to extensive acantholysis (20X, H&E). Supplementary Figure 13. Hailey-Hailey disease: A biopsy shows extensive epidermal acantholysis (40X, H&E). Supplementary Figure 14. Erythematous crusted papules on the abdomen in a patient with Grover disease. Supplementary Figure 15. Grover disease: Focal acantholytic dyskeratosis (40X, H&E). Supplementary Figure 16. Grover disease: A biopsy shows focal epidermal acantholysis and dyskeratosis (40X, H&E). Supplementary Table. Overlapping and differentiating clinical features of Darier disease, Hailey-Hailey disease, and Grover disease