Improvement of NGAL sensitivity and specificity predicting AKI after cardiac surgery

Published: 11-09-2019| Version 2 | DOI: 10.17632/fxv6kcp6j3.2
Contributor:
Giovanni Introcaso

Description

The NGAL assay performance could be improved by two consecutive plasma measurements, then with the combination of kidney biomarker with the functional marker serum creatinine at 10-18 h after surgery.

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Steps to reproduce

It was used a rapid immunofluorescent method by Biosite and a new approach for the results interpretation. The analysis on biomarker increase was obtained by a reference of value equal to 100 ng/mL. Indeed patient becomes the reference of his self.