Amurrio et al., Molecular mechanisms regulating PDE11A4 age-related liquid-liquid phase separation and its reversal by selective PDE11A4-targeted small molecules in cells and brain
Published: 6 October 2026| Version 3 | DOI: 10.17632/g3xt59g92y.3
Contributor:
Michy KellyDescription
Source data for all experiments showing PDE11A4-targeted small molecules can reverse liquid-liquid phase separation (LLPS) in vivo
Files
Institutions
- University of Maryland School of MedicineMD, Baltimore
Categories
Neuroscience, Drug Discovery, Aging, Liquid-Liquid Phase Separation
Funders
- National Institute on AgingMaryland, United States