Mapping single cell transcriptomes in kidney cancer
Published: 10 October 2022| Version 1 | DOI: 10.17632/g67bkbnhhg.1
Contributors:
Tom Mitchell, Description
Tumour behaviour is intricately dependent on the oncogenic properties of cancer cells and their multi-cellular interactions. To better understand these dependencies within the wider micro-environment, we studied over 270,000 single cell transcriptomes and 100 micro-dissected whole exomes from 12 patients with kidney tumours, prior to validation through the use of spatial transcriptomics. Tissues were sampled from multiple regions of the tumour core, the tumour-normal interface, normal surrounding tissues, and peripheral blood.
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Institutions
Wellcome Sanger Institute
Categories
Kidney Cancer, Messenger RNA