Supplemental figures: regulation of Cyp19a1 by Klf4
Published: 12-03-2019| Version 1 | DOI: 10.17632/g8zxvgp2yt.1
Contributor:
Jaesook Roh
Description
Kruppel-like factor 4 (GKLF) is rapidly and transiently increased by luteinizing hormone (LH) surge in the ovary. KLF4 inhibited Cyp19a1 expression most likely through interaction to the SF1 binding motif of Cyp19a1 promoter in periovulatory granulosa cells.