Supplemental figures: regulation of Cyp19a1 by Klf4

Published: 12 March 2019| Version 1 | DOI: 10.17632/g8zxvgp2yt.1
Contributor:
Jaesook Roh

Description

Kruppel-like factor 4 (GKLF) is rapidly and transiently increased by luteinizing hormone (LH) surge in the ovary. KLF4 inhibited Cyp19a1 expression most likely through interaction to the SF1 binding motif of Cyp19a1 promoter in periovulatory granulosa cells.

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