Concurrent Weekly Cisplatin and Simultaneous Integrated Boost Intensity-Modulated Radiotherapy of Locally Advanced Squamous Cell Carcinoma of Head and Neck
Description
This is the dataset of patients included into the phase II trial of the treatment outcomes investigation (acute and late toxicity) of concurrent weekly cisplatin and accelerated SIB IMRT in LA SCCHN at the Department of Radiation Oncology of the East Slovakia Institute of Oncology.
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The dataset was statistically analysed by the statistical program IBM SPSS. The endpoints of analysis were locoregional control rate, distant control rate, progression-free survival, overall survival and toxicity. All survival data were calculated from the date of the first fraction of radiotherapy. Cumulative survival data were calculated using the Kaplan – Meier method. Univariate and multivariate analyses using the Cox regression model were performed for the total cohort patients to determine the prognostic significance of the following factors: HPV status, cisplatin cumulative dose, overall treatment time prolongation, stage and tumor site. Univariate analysis using Cox regression model was subsequently performed for the subgroup of HPV negative SCCHN patients.