McAuliffe et al. (2021), JITC - Heterologous prime-boost vaccination targeting MAGE-type antigens promotes tumor T-cell infiltration and improves checkpoint blockade therapy

Published: 25 August 2021| Version 1 | DOI: 10.17632/h6rcgfrwry.1
Contributors:
Carol Leung,

Description

This dataset contains the raw data associated with and published in the following academic manuscript - McAuliffe et al. (2021), JITC: Heterologous prime-boost vaccination targeting MAGE-type antigens promotes tumor T-cell infiltration and improves checkpoint blockade therapy. Details on the research hypothesis of this project, descriptions of data acquired and notable findings and interpretation of the data have been described in full within the text of the published manuscript. This dataset contains raw data for all of the figures contained within the manuscript (organized and broken down as such within this dataset). This is with the exception of the high-throughput sequencing data comprising Fig. 4H, Fig. 5, Fig. S5 and Fig. S7 which has been uploaded to and made publicly available in the NCBI Gene Expression Omnibus (GEO) repository. GEO accession numbers to access these datasets have been included in the manuscript. Full descriptions of the data acquired for each figure / figure sub-part are provided in the text and figure legends of the manuscript, and information on how it was gathered and how to interpret it are contained in the materials & methods and results sections of the manuscript.

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Steps to reproduce

Details on how the data in this submission was arrived at, how it was gathered and how to reproduce it are contained within the relevant sections of the associated published manuscript.

Categories

Vaccine, Cancer Immunotherapy, Cellular Immunity, Cancer Research, Cytotoxic T-Cell, Immune Checkpoint Blockade

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