RPRD1B Recruits Repair Components to Stressed Replication Forks to Promote Survival of BRCA1-Deficient Cancer Cells

Published: 1 September 2025| Version 1 | DOI: 10.17632/h92sg7rnkj.1
Contributors:
Tien Manh Tran, Elizabeth Williamson, Aruna Jaiswal, Dominic Arris, Nhat Nguyen, Andrew Carrillo, Shaun Olsen, Kimi Kong, Montasser Shaheen, Doraid Sadadeen, Daohong Zhou, Yaxia Yuan, Shahrez Syed, Youngho Kwon, Sameer Salunkhe, Patrick Sung, Robert Hromas

Description

This dataset contains the raw microscopy images , colony formation images, western blot scans, flow cytometry images, and numerical data supporting the findings reported in the manuscript titled "RPRD1B Recruits Repair Components to Stressed Replication Forks to Promote Survival of BRCA1-Deficient Cancer Cells" (submitted to Molecular Cell). Confocal microscopy images are provided in .ome.tiff format with corresponding scale bars. Western blot data include uncropped scans labeled by figure and panel. Flow cytometry images are provided in both .fcs and .tiff format. Quantitative data are included as Excel spreadsheets. Files are organized by figure number for clarity.

Files

Institutions

  • University of Texas Health Science Center at San Antonio

Categories

Mass Spectrometry, DNA, Confocal Microscopy, Flow Cytometry, Western Blot, Slot Blot Analysis

Licence