Effects of H3.3G34V Mutation on Genomic H3K36 and H3K27 Methylation Patterns in Isogenic Pediatric Glioma Cell Lines

Name: Effects of H3.3G34V Mutation on Genomic H3K36 and H3K27 Methylation Patterns in Isogenic Pediatric Glioma Cell Lines
Creator: Tina Huang
Published: 2020-09-17T16:49:18.536Z
Keywords: Brain Tumor, Pediatric Brain Tumor, Epigenetics, Cancer Cell Line, Histone Modification, Biomedical Research

Huang, Tina

doi:10.17632/hh6x2fjkvd.1

Effects of H3.3G34V Mutation on Genomic H3K36 and H3K27 Methylation Patterns in Isogenic Pediatric Glioma Cell Lines

Published: 17 September 2020| Version 1 | DOI: 10.17632/hh6x2fjkvd.1

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Tina Huang

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This project aims to investigate the effect of histone H3G34V on H3K36me3 and H3K27me3 enrichment. Here are the raw ChIP-Seq data for KNS42 WT (unmodified), KNS42 transduced with DOX-inducible shRNA targeting H3F3A no DOX control, and KNS42 transduced with DOX-inducible shRNA targeting H3F3A +DOX.

Effects of H3.3G34V Mutation on Genomic H3K36 and H3K27 Methylation Patterns in Isogenic Pediatric Glioma Cell Lines

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