A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease - Bile acids quantification through UHPLC-MRM-MS section

Published: 25 March 2024| Version 1 | DOI: 10.17632/hmkvmsxrmb.1
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Description

The interplay between the gut microbiota, bile acids and the immune is a critical determinant in development of inflammatory bowel disease (IBD). Here we investigated the fecal bile acid profiles in murine models of colitis, through UHPLC-MRM-MS.

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Institutions

Universita degli Studi di Napoli Federico II Dipartimento di Farmacia, Universita degli Studi di Salerno Dipartimento di Farmacia, Universita degli Studi di Salerno Dipartimento di Medicina e Chirurgia

Categories

Bile Acid, Liquid Chromatography Mass Spectrometry

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