血管外膜淋巴网络相关4 个血管疾病模型单细胞转录组整合图谱

Published: 12 June 2025| Version 1 | DOI: 10.17632/jb4by4r7kj.1
Contributors:
Junru Wu, Jingjing Cai

Description

本数据集基于小鼠动脉粥样硬化、动脉导丝拉伤、自体血管移植及同种异体血管移植四种血管重构疾病模型，联合正常小鼠主动脉开展单细胞转录组测序，整合构建血管重构疾病单细胞转录组学图谱。研究重点关注血管外膜三级淋巴组织形成特征，通过细胞降维、聚类与注释分析，系统解析疾病状态下的细胞异质性。数据集目前包含总计111096个细胞，整合后数据库约检测到19849个基因表达。

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Institutions

  • Central South University Third Xiangya Hospital Department of Cardiology

Categories

Vascular Remodeling, Lymphatic System

Funders

  • National Health Commission of the People's Republic of China
    Grant ID: Noncommunicable Chronie Diseases-National Science and Technology Major Project 2023ZD0503300

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