Research on the antipruritic active ingredients of Mikania micrantha

Published: 13 June 2023| Version 1 | DOI: 10.17632/jd6xgzjjd2.1
Contributor:
Qianqian Cheng

Description

The antipruritic effect of petroleum ether, ethyl acetate, ethanol extraction site and volatile oil of Mikania micrantha was determined using a 4-aminopyridine-induced model of itching in mice. GC-MS was used to analyze the components of the antipruritic fractions, combined with mice itch-causing models to study the antipruritic effects of β-Caryophyllene and Humulene. The safety of β-Caryophyllene was preliminarily evaluated through the acute toxicity test of mice skin.

Files

Categories

Antipruritic Drug

Funding

Guangzhou Municipal Science and Technology Bureau project

2023B03J1273

Licence