Research on the antipruritic active ingredients of Mikania micrantha
Published: 13 June 2023| Version 1 | DOI: 10.17632/jd6xgzjjd2.1
Contributor:
Qianqian ChengDescription
The antipruritic effect of petroleum ether, ethyl acetate, ethanol extraction site and volatile oil of Mikania micrantha was determined using a 4-aminopyridine-induced model of itching in mice. GC-MS was used to analyze the components of the antipruritic fractions, combined with mice itch-causing models to study the antipruritic effects of β-Caryophyllene and Humulene. The safety of β-Caryophyllene was preliminarily evaluated through the acute toxicity test of mice skin.
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Categories
Antipruritic Drug
Funding
Guangzhou Municipal Science and Technology Bureau project
2023B03J1273