Mutagenesis in POLH KO and wt RPE1 cell line
Published: 10 March 2023| Version 1 | DOI: 10.17632/jkjkpvgxyd.1
Contributor:
Andrey YurchenkoDescription
We generated POLH knockouts in RPE-1 cell line and treated them with UVA, UVC, and KBrO3 to better understand mutagenesis in xeroderma pigmentosum variant (XP-V) patients. The dataset contains filtered VCF files from the experiments (GRCh37 reference genome). FASTQ raw data is available on NCBI under accession number PRJNA940340.
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Institutions
- Gustave Roussy
Categories
Mutagenesis, DNA Mutation