[Dataset] Bioactive nanostructured platforms: Physicochemical assessment of starch scaffolds hybridized with Sargassum muticum-copper oxide nanoparticles
Description
This dataset offers a comprehensive physicochemical evaluation of starch-based scaffolds functionalized with copper oxide nanoparticles (CuO NPs) synthesized using Sargassum muticum, a brown macroalga, via an eco-friendly green synthesis approach. UV-visible spectroscopy (UV-Vis) confirms CuO NP formation through characteristic plasmon resonance peaks, while Fourier-transform infrared spectroscopy (FT-IR) identifies bioactive algal compounds (e.g., polyphenols, polysaccharides) involved in nanoparticle reduction and stabilization, as well as molecular interactions (e.g., hydrogen bonding) between starch polymers and CuO NPs. X-ray diffraction (XRD) validates the crystalline structure and phase purity of the nanoparticles, and scanning electron microscopy (SEM) reveals the scaffold’s porous architecture, surface morphology, and uniform nanoparticle dispersion. Thermal gravimetric analysis (TGA) assesses thermal stability, demonstrating enhanced degradation resistance due to CuO NP reinforcement, while dynamic light scattering (DLS) quantifies hydrodynamic size, polydispersity, and colloidal stability of the NPs, critical for biocompatibility. The study highlights the role of Sargassum muticum extract in enabling sustainable CuO NP synthesis while improving scaffold functionality, including mechanical robustness, thermal resilience, and bioactive properties. These hybrid nanocomposites exhibit potential for advanced biomedical applications such as tissue engineering, antimicrobial coatings, or targeted drug delivery, where eco-conscious design and performance are paramount. By integrating algal-mediated green synthesis with advanced analytical techniques, this dataset bridges marine bioresource utilization with material innovation, offering insights into scalable, low-toxicity biomaterial development. Researchers can leverage these findings to optimize synthesis protocols, tailor scaffold porosity and crystallinity, and validate the ecological and functional benefits of marine algae-derived nanocomposites. The work underscores the synergy between green nanotechnology and biopolymer science, advancing sustainable alternatives for next-generation bioactive platforms in healthcare and environmental applications.