Experimental Data Supporting “On-Demand Biomanufacturing via Programmed SporeBot”

Description

This dataset contains the source data supporting the study “On-Demand Biomanufacturing via Programmed SporeBot.” The study develops a portable and on-demand biomanufacturing platform based on engineered Bacillus subtilis spores encapsulated within polymeric microcapsules. The deposited data include the original experimental data underlying the main and supplementary figures, covering SporeBot fabrication and stability, protein expression and secretion, system optimization, antimicrobial peptide production and activity, vaccine antigen production, virus-like particle assembly, immunogenicity, and related functional validation experiments. These data are provided to support the reproducibility and transparency of the findings reported in the associated manuscript.

Steps to reproduce

Source data are organized by figure and supplementary figure. The reported plots and statistical analyses can be reproduced from the deposited numerical data following the procedures described in the corresponding figure legends and STAR Methods section of the associated manuscript.

Institutions

• Chinese Academy of Sciences

  Beijing, Beijing

Categories

Funders

• Shenzhen Science and Technology Innovation Commission

  Shenzhen Municipal People's Government

  Guangdong, Shenzhen

Licence