Expression data from major metabolic organs of C57BL/6J mice and MIN6 cells maintained on normal or stressed conditions
Description
We studied the novel mechanism of ER quality control, ER homeostasis maintenance and functional plasticity in pancreatic β-cells to increase systemic glucose homeostasis against progression of type 2 diabetes. In RNA-Seq dataset, we provided islets' RNA-Seq for C57BL/6J wildtype mice on 2-month high-fat diet and on normal chow; we also provided 8 different metabolic tissues' RNA-Seq for C57BL/6J wildtype mice on normal chow; RNA were collected from shAp2s1 MIN6 cells and shScrb control cells on normal culturing condition. In proteomics dataset, we provided proteome analysis on MIN6 cells and supernatant on normal and stressed culturing conditions. Original computational code for image processing were deposited in this dataset. All the algorithms were implemented with OpenCV and Numpy library in Python.