Safety and efficacy study of cross-linked hyaluronic acid 30 mg/ml for facial filler
Description
Introduction: aging is a multifactorial process that affects both the functionality and aesthetics of the body, including the skin, influenced by intrinsic (genetic) and extrinsic (environmental) factors. Fillers, especially those based on hyaluronic acid (HA), are the most preferred in aesthetic procedures due to their efficacy, safety, and ease of use. In the midface, the most visible signs of aging, such as wrinkles and furrows, are often treated with cross-linked HA (CHA), recognized worldwide for its ability to correct folds and restore volume. Its resorption depends on time and individual and environmental factors, offering lasting results and reducing complications compared to other methods. Objectives: to evaluate the efficacy and safety of Cientific Hyaluronic Facial Implant 30® as a filler in various areas of the face and its longevity. Materials and methods: an observational, longitudinal, multicenter, prospective study involving 55 patients, aged 23–78 years, average age 45; 84% were female (46) and 16% male (9). Patients ranged from Fitzpatrick type I to IV. The study was conducted between January 2022 and April 2023. The treated areas were: nasolabial folds, lip augmentation and contouring, upper lip wrinkles, and cheekbones. Crosslinked hyaluronic acid (CH) 30 mg/ml (Cientific Hyaluronic Facial Implant 30®, CH30) was used for facial fillers. Results: the average duration of the biphasic AHR treatment was up to 8 months, with the possibility of extending it to one year with appropriate reapplications. The duration of these effects also depended on the patient's age and skin condition, as well as certain habits such as sun exposure or smoking. Conclusions: Cientific Hyaluronic Facial Implant 30® is a safe product. Adverse effects resolved within 7 days in 97% of cases and within 14 days in the remaining cases. Regarding its effectiveness as a filler, its average duration at the implant site was up to 8 months, depending on the patient's age and skin condition.
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- Allanmar International Company S.R.L