Large-scale integrative de novo assembly of 26,848 human transcriptomes reveals cancer-specific isoform dysregulation at full-length resolution

Name: Large-scale integrative de novo assembly of 26,848 human transcriptomes reveals cancer-specific isoform dysregulation at full-length resolution
Creator: Junghoon Shin
Published: 2026-06-16T23:47:18.040Z
Keywords: Transcriptome, Metadata

Shin, Junghoon; kang, hyeongu; Shim, Hyeran; Yoo, Jiye; Yang, Jun Ok; Park, Kyu Joo; Kim, Tae-You; Yu, Chang Sik; Kim, Young-Joon; Choi, Jung Kyoon

doi:10.17632/krjt35982r.1

Large-scale integrative de novo assembly of 26,848 human transcriptomes reveals cancer-specific isoform dysregulation at full-length resolution

Published: 16 June 2026| Version 1 | DOI: 10.17632/krjt35982r.1

Contributors:

Junghoon Shin, hyeongu kang, Hyeran Shim, Jiye Yoo, Jun Ok Yang, Kyu Joo Park, Tae-You Kim, Chang Sik Yu, Young-Joon Kim, Jung Kyoon Choi

Description

stringtie_transcript_filtered.fst: StringTie-assembled annotation of filter-passed transcripts stringtie_exon_filtered.fst: Exon annotation for stringtie_transcript_filtered.fst stringtie_cds_filtered.fst: Coding sequence annotation for stringtie_transcript_filtered.fst noncoding_transcripts.tsv: Transcripts predicted to have lost coding potential dtu_lmerfit_filtered_ihw.rds: Differential transcript usage (DUT) results, including p-values and summary statistics sample_annotation.tsv: Metadata for all available samples (n=26,848)

Large-scale integrative de novo assembly of 26,848 human transcriptomes reveals cancer-specific isoform dysregulation at full-length resolution

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