Protease-mediated processing of Argonaute proteins controls small RNA association - Gudipati et al.

Published: 1 February 2021| Version 1 | DOI: 10.17632/m5yskrk6k4.1
Contributor:
Helge Grosshans

Description

Imaging data (Microscopy and Western blot) for Gudipati et al, 2021. Publication containing these data reveal a role of the N-terminal dipeptidase DPF-3 in processing C. elegans Argonaute proteins WAGO-1 and WAGO-3. Loss of processing causes up regulation of transposable elements, DNA damage and thus sperm loss and sterility at elevated temperature. This is due to altered 22G RNA profiles

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Institutions

Friedrich Miescher Institute for Biomedical Research

Categories

Molecular Biology, Dipeptidyl Peptidase, Small Interfering RNA, Fertility, Biological Development

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