Plasma metabolomics in spinal tuberculosis patients and healthy controls

Published: 24 July 2023| Version 2 | DOI: 10.17632/m6dvnphgj5.2
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Description

This study aimed to conduct a non-targeted metabolomic analysis of plasma from patients with spinal tuberculosis (STB) to systematically elucidate the metabolomic alterations associated with STB. From January 2020 to January 2022, 30 patients with spinal tuberculosis (STBs) clinically diagnosed at the General Hospital of Ningxia Medical University and 30 age- and sex-matched healthy controls (HCs) were selected for this study. Using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS) based metabolomics, we analyzed the metabolic profiles of 60 plasma samples.

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Categories

Metabolomics, Tuberculosis, Mycobacterium tuberculosis

Funding

Key Research and Development Program of Ningxia

2022BEG03099

National Natural Science Foundation of China

81860395

National Natural Science Foundation of China

82260436

National College Students Innovation and Entrepreneurship Training Program

202210752008

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