Gene expression profile at single cell level of fibroblasts from untreated (UT) and imiquimod (IMQ)-induced mouse skin.

Published: 15 January 2024| Version 1 | DOI: 10.17632/n3b6vwyt7b.1
Contributor:
Xiaojie Cai

Description

We used single-cell RNA sequencing (scRNA-seq) to analyze the heterogeneity of dermal fibroblasts in homeostasis and skin inflammation. Dermal fibroblasts of the UT/IMQ-induced PdgfraDreER-tdTomato mice were isolated by Fluorescence-activated cell sorting (FACS) according to the presence or absence of tdTomato signal and analyzed using scRNA-seq.

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Categories

Fibroblast, Pathophysiology of Psoriasis, Single-Cell Transcriptomics

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