Small proteins modulate ion channel-like ACD6 to regulate immunity in Arabidopsis thaliana

Published: 13 October 2023| Version 1 | DOI: 10.17632/p26vr5tjt4.1
Contributors:
Jun-bin Chen,
,
, Benjamin Neuhaeuser, mingyu wang, Michael Thelen,
,
,
, Kavita Venkataramani, Moises Exposito-Alonso,
, Jakob Keck, A. Cristina Barragan, Rebecca Schwab, Ulrich Lutz,
,
, Uwe Ludewig, Detlef Weigel,

Description

The ankyrin-repeat transmembrane protein ACD6 was identified two decades ago, but its exact biochemical function has remained enigmatic. Chen et al. show that ACD6 is a bona fide regulator of calcium influx using heterologous systems and calcium reporters in plants, and that this activity can be further enhanced by a MHA1L peptide ligand.

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Categories

Innate Immunity, Calcium Channel, Pattern Perception

Funders

  • Science Foundation of Ministry of Education of China
    China
    Grant ID: the 111 Project B13006
  • Ministry of Science and Technology of the People's Republic of China
    Beijing, China
    Grant ID: 2022YFD1201802
  • the 2115 Talent Development Program of China Agricultural University
    Grant ID: 2020RC013
  • EMBO Long-term Fellowship
    Grant ID: 969-2016
  • HFSP Long-term Fellowship
    Grant ID: LT000314/2017-L
  • USDA NIFA Postdoctoral Fellowship Award
    Grant ID: 2021-67012-35140
  • DFG
    Grant ID: NE 1727/2-2
  • the Ministry of Science, Research and Arts Baden-Württemberg through the Regio Research Alliance “Yield Stability in Dynamic Environments”
    Grant ID: NA
  • Max Planck Society
    Bavaria, Germany
    Grant ID: NA

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