Salidroside project
Published: 22 January 2026| Version 2 | DOI: 10.17632/p8hw5rt8k4.2
Contributors:
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The project tested primarily the influence of salidroside on cytochrome P450 metabolic activities and a possible mechanism of induced changes. The rats were treated with salidroside at the doses from 5 to 45 mg/kg/day for 7 consecutive days. The liver microsomes were isolated and tested for P450 metabolic activities with specific substrates. In vitro inhibition studies with human liver microsomes and naive rat liver microsomes were also performed.
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Institutions
- Univerzita KarlovaPraha
- Masarykova univerzitaJihomoravský, Brno
Categories
Pharmacokinetics, Animal Pharmacology, Cytochrome P450