Incidence, clinical characteristics and risk factors for infantile hemangioma ulceration after oral propranolol initiation: a retrospective study
Description
Some patients with infantile hemangioma (IH) still develop ulcerations during oral propranolol, but these IH ulcerations have not been systematically studied.Our study aimed to analyze the incidence, clinical features and risk factors associated with IH ulceration after oral propranolol initiation, providing insights for identifying patients at high risk of IH ulceration and improving ulceration prevention strategies. We evaluated 470 patients with IH who received oral propranolol and 51 patients with nonintervention IH ulceration; 24 (5.1%) developed IH ulceration during oral propranolol. Mixed, segmental and indeterminate subtypes were independent risk factors for IH ulceration after oral propranolol initiation. These findings underscore the importance of enhanced surveillance and preventive local care in infants with high-risk morphological features.
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Institutions
- West China Hospital of Sichuan UniversitySichuan, Chengdu