Joint Distribution of Intermitotic Lifetimes of Generation 1 and 2 Sister Cells: The Effect of Bandwidth

Description

These animations display the empirical joint distribution obtained via Gaussian kernel smoothing across bandwidths from 0.10 to 0.95 (where h is the bandwidth parameter). Note the positive correlation between the sister cells' lifespans, which suggests a mechanism of cellular inheritance. This example is adapted from Figure 6 of Korsnes et al., "Lineage-Resolved Lifetime Modelling Reveals Potential Quiescence and Synchronization among MDA-MB-468 Breast Cancer Cells," Frontiers in Cell and Developmental Biology (2026).

Institutions

• Norwegian University of Science and Technology

  Trøndelag, Trondheim
• Nord University

  Nordland, Bodø

Categories

Licence