Data for: Democratizing LYTACs—A Modular Click Chemistry Platform for the Rapid Assembly of Lysosome-Targeting Chimeras

Description

Raw .txt MALDI files organized by date of acquisition. MALDI analysis script in R. The data were analyzed using the MALDIquant package in RStudio 2024.12.1 Build 563. ChatGPT-4o (OpenAI) was used to assist in the writing of the analysis script. Gibb, S.; Strimmer, K. Maldiquant: A Versatile R Package for the Analysis of Mass Spectrometry Data. Bioinformatics 2012, 28 (17), 2270–2271. https://doi.org/10.1093/bioinformatics/bts447. Also included are data from the in vitro flow cytometry and live-cell analysis experiments as .prism files. For the live-cell analysis dataset, representative videos are included as well.

Institutions

• Stanford University

  California, Stanford
• Howard Hughes Medical Institute

  Maryland, Chevy Chase
• University of Notre Dame

  Indiana, Notre Dame

Categories

Funders

• National Institutes of Health

  Bethesda

  Grant ID: GM058867
• University of Notre Dame

  Notre Dame

  Grant ID: Startup Grant
• Howard Hughes Medical Institute

  Chevy Chase

  Grant ID: CC34977

Licence