SIRT2 transgenic over-expression does not impact lifespan in mice - associated data
Published: 2 November 2023| Version 1 | DOI: 10.17632/rdwgnfh23g.1
Contributor:
Description
Raw data and accompanying R code for analysis and creating figures for the manuscript "SIRT2 transgenic overexpression does not impact lifespan in mice" by Wu LE et al, Aging Cell 2023 (doi: 10.1111/acel.14027). This was a study of lifespan and age-related healthspan in a strain of SIRT2 transgenic mice, showing no impact from the SIRT2 transgene.
Files
Steps to reproduce
Open the accompanying R script in RStudio in a new root folder, where the accompanying CSV files should be dropped. The code is annotated to recreate each figure and analysis, highlight each section and hit ctrl-enter to run code.
Institutions
Victor Chang Cardiac Research Institute, University of New South Wales
Categories
Aging, Life-Span, Healthy Ageing, 13C NMR Spectroscopy
Funding
National Health and Medical Research Council
APP1066172
National Health and Medical Research Council
APP1127821
American Federation for Aging Research
New Investigator award
AM Process Data Template
| Additive Manufacturing Process | NA |
| Process Parameters | NA |
| Process Date | 2023-11-02T00:00:00.000Z |
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| Type | Public Domain |
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Publications
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| Publication Title | SIRT2 transgenic over‐expression does not impact lifespan in mice |
| Publication DOI | 10.1111/acel.14027 |
| Citation | Wu LE et al "SIRT2 transgenic over‐expression does not impact lifespan in mice", Aging Cell 2023 |
| Authors | Wu, Lindsay E. |
AM Sample Data Template
| Sample ID | NA |
| Date | 2023-11-02T00:00:00.000Z |
| Alloy Type | Fe-Base |
| Alloy composition | NA |
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MURI/AUSMURI University
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| University | UNSW Sydney |
| Address | University of New South Wales, Kensington 2052, NSW, Australia |
| Acknowledgement | LEW is supported by an American Federation for Aging Research (AFAR)/Hevolution New Investigator award. This work was supported by the National Health and Medical Research Council (NHMRC) of Australia, through project grant APP1066172 and fellowship APP1127821. |
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