Intergrated Multi-omics Sequencing Reveals Metabolic Reprograms in the Progression of ccRCC_spatial_multiome

Published: 26 June 2023| Version 1 | DOI: 10.17632/rhh5rpvxhd.1
Contributor:
Junyi Hu

Description

100 samples from treatment-naive ccRCC patients and 50 matched normal adjacent tissues (NATs) were profiled with whole exon sequencing (WES), whole transcriptome sequencing (WTS), data-independent acquisition (DIA)-based proteome and untargeted metabolome technology to identify the general molecular characteristics of the TJ-RCC cohort. Single-nucleic RNA sequencing, single-nucleic multiome, spatial transcriptome and spatial metabolome were performed on part of these 100 tumors to detail the ITH inside ccRCC.

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Renal Cell Carcinoma

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